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The kinetics of inhibition of rat recombinant heteromeric α1β glycine receptors by the low-affinity antagonist SR-95531

The GABA(A) antagonist SR-95531 (gabazine) is known to block glycine receptors, albeit with low affinity. We have studied the effect of SR-95531 on rat recombinant α1β glycine receptors expressed in human embryonic kidney (HEK293) cells by recording macroscopic currents elicited by rapid glycine app...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beato, Marco, Burzomato, Valeria, Sivilotti, Lucia G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075427/
https://ncbi.nlm.nih.gov/pubmed/17218350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.126888
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