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Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA(2)α activity
The prevailing hypothesis that a signalling pathway involving cPLA(2)α is required to enhance the gating of the voltage-gated proton channel associated with NADPH oxidase was tested in human eosinophils and murine granulocytes. This hypothesis invokes arachidonic acid (AA) liberated by cPLA(2)α as a...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2075394/ https://ncbi.nlm.nih.gov/pubmed/17185330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.124248 |
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