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Calcium sparklets regulate local and global calcium in murine arterial smooth muscle

In arterial smooth muscle, protein kinase Cα (PKCα) coerces discrete clusters of L-type Ca(2+) channels to operate in a high open probability mode, resulting in subcellular domains of nearly continual Ca(2+) influx called ‘persistent Ca(2+) sparklets’. Our previous work suggested that steady-state C...

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Autores principales: Amberg, Gregory C, Navedo, Manuel F, Nieves-Cintrón, Madeline, Molkentin, Jeffery D, Santana, Luis F
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075382/
https://ncbi.nlm.nih.gov/pubmed/17158168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.124420
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