Ryanodine receptor type 2 deficiency changes excitation–contraction coupling and membrane potential in urinary bladder smooth muscle

The possibility that the ryanodine receptor type 2 (RyR2) can function as the major Ca(2+)-induced Ca(2+) release (CICR) channel in excitation–contraction (E-C) coupling was examined in smooth muscle cells (SMCs) isolated from urinary bladder (UB) of RyR2 heterozygous KO mice (RyR2(+/−)). RyR2 mRNA...

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Hlavní autoři: Hotta, Shingo, Morimura, Kozo, Ohya, Susumu, Muraki, Katsuhiko, Takeshima, Hiroshi, Imaizumi, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2007
Témata:
Cellular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075324/
https://ncbi.nlm.nih.gov/pubmed/17363382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.130302
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