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Potential Use of Toxic Thermolabile Proteins To Study Protein Quality Control Systems

SulA is an Escherichia coli division inhibitor with a short half-life whose accumulation results in filamentation. Here, we show that SulA is thermally unstable and forms aggregates at elevated temperatures. This property enables the selection of isolates with mutated protein quality control systems...

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Bibliografski detalji
Glavni autori: Mizrahi, Itzhak, Dagan, Michael, Biran, Dvora, Ron, Eliora Z.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074907/
https://ncbi.nlm.nih.gov/pubmed/17644648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01067-07
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