P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo.

We examined whether the increased expression of P-glycoprotein (P-gp) encoded by the human multidrug resistance gene MDR1 is related to the acquired multidrug resistance of lung cancer in vivo. We estimated the chemosensitivity of lung cancer xenografts (LC-6, adenocarcinoma; Lu-24, small-cell cance...

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Autors principals: Abe, Y., Ohnishi, Y., Yoshimura, M., Ota, E., Ozeki, Y., Oshika, Y., Tokunaga, T., Yamazaki, H., Ueyema, Y., Ogata, T., Tamaoki, N., Nakamura, M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074809/
https://ncbi.nlm.nih.gov/pubmed/8980392
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