K-ras mutations and HLA-DR expression in large bowel adenomas.

A total of 72 sporadic colorectal adenomas in 56 patients were studied for the presence of point mutations in codons 12 and 13 of the K-ras gene and for HLA-DR antigen expression related to clinicopathological variables. Forty K-ras mutations in 39 adenomas were found (54%): 31 (77%) in codon 12 and...

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Autors principals: Norheim Andersen, S., Breivik, J., Løvig, T., Meling, G. I., Gaudernack, G., Clausen, O. P., Schjölberg, A., Fausa, O., Langmark, F., Lund, E., Rognum, T. O.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074621/
https://ncbi.nlm.nih.gov/pubmed/8679466
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