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Villous, hypermucinous mucosa in long standing ulcerative colitis shows high frequency of K-ras mutations
BACKGROUND—K-ras mutation is one of the first genetic alterations in classical colorectal carcinogenesis. AIMS—To investigate the role of K-ras mutations in carcinogenesis, in long standing ulcerative colitis. METHODS—A total of 161 microdissected and 100 DNA samples from 13 patients were analysed f...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1727707/ https://ncbi.nlm.nih.gov/pubmed/10517904 |
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