ToxR proteins with substitutions in residues conserved with OmpR fail to activate transcription from the cholera toxin promoter.

The ToxR protein of Vibrio cholerae is an integral membrane protein that coordinately regulates the expression of virulence genes required for successful infection. ToxR has been shown to bind directly to and activate transcription of the cholera toxin (ctx) promoter. Within the amino-terminal cytop...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Ottemann, K M, DiRita, V J, Mekalanos, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1400230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.21.6807-6814.1992
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