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Effect of Rds Abundance on Cone Outer Segment Morphogenesis, Photoreceptor Gene Expression, and Outer Limiting Membrane Integrity

We examined the molecular, structural, and functional consequences on cone photoreceptors of the neural retinal leucine zipper knockout (Nrl(−/−)) mice when only one allele of retinal degeneration slow (Rds) is present (Rds(+/−)/Nrl(−/−)). Quantitative RT-PCR and immunoblot analysis were used to ass...

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Auteurs principaux: FARJO, RAFAL, FLIESLER, STEVEN J., NAASH, MUNA I.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072815/
https://ncbi.nlm.nih.gov/pubmed/17722028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.21476
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