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Effect of Rds Abundance on Cone Outer Segment Morphogenesis, Photoreceptor Gene Expression, and Outer Limiting Membrane Integrity

We examined the molecular, structural, and functional consequences on cone photoreceptors of the neural retinal leucine zipper knockout (Nrl(−/−)) mice when only one allele of retinal degeneration slow (Rds) is present (Rds(+/−)/Nrl(−/−)). Quantitative RT-PCR and immunoblot analysis were used to ass...

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Detalhes bibliográficos
Main Authors: FARJO, RAFAL, FLIESLER, STEVEN J., NAASH, MUNA I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072815/
https://ncbi.nlm.nih.gov/pubmed/17722028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.21476
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