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The Influence of the Iso-electric Point of L-Asparaginase upon its Persistence in the Blood
A series of chemically modified Erwinia carotovora asparaginases was prepared with iso-electric points (pI) from 3·3-9·7. The half-life of each modified enzyme in the circulating blood of rabbits was closely related to its pI. Half-life increased with pI from about 5 min. at pI 3·3 to a maximum of 1...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1971
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2072399/ https://ncbi.nlm.nih.gov/pubmed/4944363 |
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