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Effects of Chlorimipramine on Human Cells in Tissue Culture

Chlorimipramine is toxic to human skin fibroblasts in culture at concentrations as low as 10 μg./ml. if treatment exceeds 1 hr. The effects are manifest in arrest of mitosis at metaphase and subsequent cell death. The drug inhibits oxygen uptake by cells in an oxygen electrode system, suggesting tha...

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Detalhes bibliográficos
Main Authors: Wilkie, D., Delhanty, Joy
Formato: Artigo
Idioma:Inglês
Publicado em: 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072219/
https://ncbi.nlm.nih.gov/pubmed/4321629
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