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Effects of mitochondrial inhibition by chloramphenicol on the mitotic cycle of human cell cultures

Chloramphenicol, at concentrations of 500 μg/ml, had a marked inhibitory effect on mitoses in human fibroblasts. Metaphase and G2 appeared to be particularly sensitive to the action of the drug. With concentrations of 1000 μg/ml, or with 500 μg/ml after prolonged exposure, the cells did not reach G2...

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Autores principales: Mittwoch, Ursula, Kirk, D. J., Wilkie, D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1974
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1013139/
https://ncbi.nlm.nih.gov/pubmed/4431031
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