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The two single nucleotide polymorphisms in the H37/RBM5 tumour suppressor gene at 3p21.3 correlated with different subtypes of non-small cell lung cancers

Allele loss and genetic alteration in chromosome 3p, particularly in 3p21.3 region, are the most frequent and the earliest genomic abnormalities found in lung cancer. Multiple 3p21.3 genes exhibit various degrees of tumour suppression activity suggesting that 3p21.3 genes may function as an integrat...

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Autors principals: Oh, Juliana J., Koegel, Ashley, Phan, Diana T., Razfar, Ali, Slamon, Dennis J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071930/
https://ncbi.nlm.nih.gov/pubmed/17606309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2007.05.020
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