Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Fatty acids (FAs) and their derivatives are essential cellular metabolites whose concentrations must be closely regulated. This implies that regulatory circuits exist which can sense changes in FA levels. Indeed, the peroxisome proliferator-activated receptor α (PPARα) regulates lipid homeostasis an...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Forman, Barry Marc, Chen, Jasmine, Evans, Ronald M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9113986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4312
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