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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Fatty acids (FAs) and their derivatives are essential cellular metabolites whose concentrations must be closely regulated. This implies that regulatory circuits exist which can sense changes in FA levels. Indeed, the peroxisome proliferator-activated receptor α (PPARα) regulates lipid homeostasis an...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Forman, Barry Marc, Chen, Jasmine, Evans, Ronald M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9113986/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4312
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