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Electrophysiological and other effects on rabbit hearts of CCI22277, a new steroidal antiarrhythmic drug.

1 CCI22277 (methyl 2 beta-ethoxy-2 alpha-hydroxy-11 alpha-(3-methylbutylamino)-5 alpha-androstane-17 beta-carboxylate hydrochloride) is an aminosteroid with antiarrhythmic properties in animal models. 2 It slowed significantly conduction velocity and spontaneous frequency. 3 CI22277 was a local anae...

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Detalhes bibliográficos
Main Authors: Campbell, T. J., Vaughan Williams, E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071789/
https://ncbi.nlm.nih.gov/pubmed/7093588
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