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Effects on rabbit nodal, atrial, ventricular and Purkinje cell potentials of a new antiarrhythmic drug, cibenzoline, which protects against action potential shortening in hypoxia.

1 The effects of cibenzoline (UP 339-01), a new anti-arrhythmic drug, have been investigated in various cardiac tissues. 2 UP 339-01 produced a bradycardia, due partly to prolongation of the intracellularly recorded sinus node action potential duration (APD) and partly to depression of the maximum r...

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Detalhes bibliográficos
Main Authors: Millar, J. S., Vaughan Williams, E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071575/
https://ncbi.nlm.nih.gov/pubmed/7066601
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