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In vivo receptor binding of the opiate partial agonist, buprenorphine, correlated with its agonistic and antagonistic actions.

1 In order to gain more insight into the mechanisms behind the actions of opiate partial agonists, an analysis of the dual agonist/antagonist properties of the partial agonist, buprenorphine, was made in conjunction with in vivo binding studies on the drug in the rat. 2 Buprenorphine revealed a bell...

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Autors principals: Dum, J. E., Herz, A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071750/
https://ncbi.nlm.nih.gov/pubmed/6271322
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