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In vivo receptor binding of the opiate partial agonist, buprenorphine, correlated with its agonistic and antagonistic actions.

1 In order to gain more insight into the mechanisms behind the actions of opiate partial agonists, an analysis of the dual agonist/antagonist properties of the partial agonist, buprenorphine, was made in conjunction with in vivo binding studies on the drug in the rat. 2 Buprenorphine revealed a bell...

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Detalhes bibliográficos
Main Authors: Dum, J. E., Herz, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071750/
https://ncbi.nlm.nih.gov/pubmed/6271322
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