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Inhibition of prostaglandin E1-responsive platelet adenylate cyclase by heparin: a study of the mechanism of inhibition and its relevance to platelet aggregation

1 Heparin can produce platelet aggregation in vitro and in vivo; it has been proposed that this may be due to the reported inhibition of the prostaglandin E(1) (PGE(1))-stimulated adenylate cyclase of the platelet by heparin. 2 The effect of heparin on the cyclic adenosine 3′,5′-monophosphate (cycli...

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Autori principali: Amirrasooli, H., Mac Neil, S., Tomlinson, S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1981
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071710/
https://ncbi.nlm.nih.gov/pubmed/7248663
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