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alpha 1-adrenoceptors can mediate chronotropic responses in the rat heart.

In the pithed rat, amidephrine a "selective" alpha 1-adrenoceptor agonist, evokes a positive chronotropic response. This response can be antagonized by prazosin but not by propranolol or by rauwolscine. Similarly, part of the chronotropic response to cardioaccelerator nerve stimulation is...

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Autors principals: Flavahan, N. A., McGrath, J. C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071683/
https://ncbi.nlm.nih.gov/pubmed/6265015
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