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alpha 1-adrenoceptor activation can increase heart rate directly or decrease it indirectly through parasympathetic activation.

1 The chronotropic effects of alpha- and beta-adrenoceptor agonists were investigated in the pithed rat. 2 The beta-adrenoceptor agonist, isoprenaline, produced only a positive chronotropic response. alpha 1-Adrenoceptor agonists, phenylephrine and amidephrine, produced positive and negative chronot...

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Detalhes bibliográficos
Main Authors: Flavahan, N. A., McGrath, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044592/
https://ncbi.nlm.nih.gov/pubmed/6128039
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