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Antifibrillatory efficacy of encainide, loracainide and ORG 6001 compared with lignocaine in isolated hearts of rabbits and guinea-pigs.

1 In Langendorff-perfused rabbit hearts, electrical stimulation threshold and ventricular fibrillation threshold (VFT) were measured by applying rectangular impulses of 3 ms duration and increasing current at frequencies of 4 and 20 Hz respectively. 2 Perfusion with lignocaine or one of three new an...

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Detalhes bibliográficos
Main Authors: Almotrefi, A. A., Baker, J. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071657/
https://ncbi.nlm.nih.gov/pubmed/6786403
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