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Investigation of the antifibrillatory activity of some anticonvulsant gamma-aminobutyric acid-transaminase inhibitors in the rabbit isolated heart: comparison with phenytoin and mexiletine.

1 The electrical stimulation and ventricular fibrillation thresholds were measured in the Langendorff-perfused rabbit heart by application of rectangular impulses of 3 ms duration and increasing current at frequencies of 4 and 20 Hz respectively. 2 Perfusion with either phenytoin or mexiletine produ...

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Detalhes bibliográficos
Main Authors: Almotrefi, A. A., Baker, J. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044442/
https://ncbi.nlm.nih.gov/pubmed/7470766
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