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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development

We have isolated and characterized a cDNA for a novel Per-Arnt/AhR-Sim basic helix–loop–helix (bHLH-PAS) factor that interacts with the Ah receptor nuclear translocator (Arnt), and its predicted amino acid sequence exhibits significant similarity to the hypoxia-inducible factor 1α (HIF1α) and Drosop...

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Autori principali: Ema, Masatsugu, Taya, Shinichiro, Yokotani, Noboru, Sogawa, Kazuhiro, Matsuda, Youichi, Fujii-Kuriyama, Yoshiaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20712/
https://ncbi.nlm.nih.gov/pubmed/9113979
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