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Use of ultrasound pulses combined with Definity(®) for targeted blood-brain barrier disruption: a feasibility study

We have developed a method to use low-intensity focused ultrasound pulses combined with an ultrasound contrast agent to produce temporary blood-brain barrier disruption (BBBD). This method could provide a means for the targeted delivery of drugs or imaging agents into the brain. All of our previous...

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Bibliographic Details
Main Authors: McDannold, Nathan, Vykhodtseva, Natalia, Hynynen, Kullervo
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2066193/
https://ncbi.nlm.nih.gov/pubmed/17337109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2006.10.004
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