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Are There Rearrangement Hotspots in the Human Genome?

In a landmark paper, Nadeau and Taylor [18] formulated the random breakage model (RBM) of chromosome evolution that postulates that there are no rearrangement hotspots in the human genome. In the next two decades, numerous studies with progressively increasing levels of resolution made RBM the de fa...

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Detalles Bibliográficos
Main Authors: Alekseyev, Max A, Pevzner, Pavel A
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065889/
https://ncbi.nlm.nih.gov/pubmed/17997591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030209
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