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Are There Rearrangement Hotspots in the Human Genome?
In a landmark paper, Nadeau and Taylor [18] formulated the random breakage model (RBM) of chromosome evolution that postulates that there are no rearrangement hotspots in the human genome. In the next two decades, numerous studies with progressively increasing levels of resolution made RBM the de fa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2065889/ https://ncbi.nlm.nih.gov/pubmed/17997591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030209 |
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