ロード中...
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis
The physiological role of the mitotic checkpoint protein Bub1 is unknown. To study this role, we generated a series of mutant mice with a gradient of reduced Bub1 expression using wild-type, hypomorphic, and knockout alleles. Bub1 hypomorphic mice are viable, fertile, and overtly normal despite weak...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2007
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064762/ https://ncbi.nlm.nih.gov/pubmed/17938250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706015 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|