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p66(Shc) mediates anoikis through RhoA

Detachment of parenchymal cells from a solid matrix switches contextual cues from survival to death during anoikis. Marked shape changes accompany detachment and are thought to trigger cell death, although a working model to explain the coordination of attachment sensation, shape change, and cell fa...

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Detalhes bibliográficos
Main Authors: Ma, Zhenyi, Myers, David P., Wu, Ru Feng, Nwariaku, Fiemu E., Terada, Lance S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064727/
https://ncbi.nlm.nih.gov/pubmed/17908916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706097
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