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β4 integrin activates a Shp2–Src signaling pathway that sustains HGF-induced anchorage-independent growth

Despite being a cell–matrix adhesion molecule, β4 integrin can prompt the multiplication of neoplastic cells dislodged from their substrates (anchorage-independent growth). However, the molecular events underlying this atypical behavior remain partly unexplored. We found that activation of the Met r...

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Detalles Bibliográficos
Main Authors: Bertotti, Andrea, Comoglio, Paolo M., Trusolino, Livio
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064708/
https://ncbi.nlm.nih.gov/pubmed/17158954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605114
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