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Metabolic regulation of Akt: roles reversed

The respiration-deficient, highly glycolytic metabolic phenotype of cancer cells known as the “Warburg effect” has been appreciated for many years. A new study (see Pelicano et al. on p. 913 of this issue) demonstrates that respiration deficiency caused by mitochondrial mutation or hypoxia may direc...

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Detalhes bibliográficos
Main Authors: Coloff, Jonathan L., Rathmell, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064693/
https://ncbi.nlm.nih.gov/pubmed/17158959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610119
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