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RNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesis

Vigilin/Scp160p/DDP1 is a ubiquitous and highly conserved protein containing 15 related, but non-identical, K-homology (KH) nucleic acid binding domains. While its precise function remains unknown, proposed roles for vigilin include chromosome partitioning at mitosis, facilitating translation and tR...

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Detalhes bibliográficos
Main Authors: Goolsby, Kathryn M., Shapiro, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC206468/
https://ncbi.nlm.nih.gov/pubmed/14500828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg768
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