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Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3

Skin lies at the interface between the complex physiology of the body and the external environment. This essential epidermal barrier, composed of cornified proteins encased in lipids, prevents both water loss and entry of infectious or toxic substances. We uncover that the transcription factor GATA-...

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Библиографические подробности
Главные авторы: de Guzman Strong, Cristina, Wertz, Philip W., Wang, Chenwei, Yang, Fan, Meltzer, Paul S., Andl, Thomas, Millar, Sarah E., Ho, I-Cheng, Pai, Sung-Yun, Segre, Julia A.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064601/
https://ncbi.nlm.nih.gov/pubmed/17116754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605057
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