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Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3

Skin lies at the interface between the complex physiology of the body and the external environment. This essential epidermal barrier, composed of cornified proteins encased in lipids, prevents both water loss and entry of infectious or toxic substances. We uncover that the transcription factor GATA-...

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Detalhes bibliográficos
Main Authors: de Guzman Strong, Cristina, Wertz, Philip W., Wang, Chenwei, Yang, Fan, Meltzer, Paul S., Andl, Thomas, Millar, Sarah E., Ho, I-Cheng, Pai, Sung-Yun, Segre, Julia A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064601/
https://ncbi.nlm.nih.gov/pubmed/17116754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605057
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