Conditional deletion of β1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality

Conditional deletion of β1 integrins in the intestinal epithelium, unlike in epidermal and mammary epithelia, of mice does not result in decreased cell adhesion and proliferation, but instead causes a profound increase in epithelial proliferation with dysplasia and polypoid structures. The increased...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jones, Robert G., Li, Xiufen, Gray, Phillip D., Kuang, Jinqiu, Clayton, Frederic, Samowitz, Wade S., Madison, Blair B., Gumucio, Deborah L., Kuwada, Scott K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2006
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064526/
https://ncbi.nlm.nih.gov/pubmed/17088430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602160
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