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Hedgehog signaling controls homeostasis of adult intestinal smooth muscle

The Hedgehog (Hh) pathway plays multiple patterning roles during development of the mammalian gastrointestinal tract, but its role in adult gut function has not been extensively examined. Here we show that chronic reduction in the combined epithelial Indian (Ihh) and Sonic (Shh) hedgehog signal lead...

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Detalhes bibliográficos
Main Authors: Zacharias, William J., Madison, Blair B., Kretovich, Katherine E., Walton, Katherine D., Richards, Neil, Udager, Aaron M., Li, Xing, Gumucio, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118277/
https://ncbi.nlm.nih.gov/pubmed/21545794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.04.025
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