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Differential phosphorylation of NG2 proteoglycan by ERK and PKCα helps balance cell proliferation and migration

Two distinct Thr phosphorylation events within the cytoplasmic domain of the NG2 proteoglycan help regulate the cellular balance between proliferation and motility. Protein kinase Cα mediates the phosphorylation of NG2 at Thr(2256), resulting in enhanced cell motility. Extracellular signal–regulated...

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Bibliografski detalji
Glavni autori: Makagiansar, Irwan T., Williams, Scott, Mustelin, Tomas, Stallcup, William B.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064431/
https://ncbi.nlm.nih.gov/pubmed/17591920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612084
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