Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA

Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria–localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and i...

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Main Authors: Poncet, Delphine, Pauleau, Anne-Laure, Szabadkai, Gyorgy, Vozza, Angelo, Scholz, Sebastian R., Le Bras, Morgane, Brière, Jean-Jacques, Jalil, Abdelali, Le Moigne, Ronan, Brenner, Catherine, Hahn, Gabriele, Wittig, Ilka, Schägger, Hermann, Lemaire, Christophe, Bianchi, Katiuscia, Souquère, Sylvie, Pierron, Gerard, Rustin, Pierre, Goldmacher, Victor S., Rizzuto, Rosario, Palmieri, Ferdinando, Kroemer, Guido
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064390/
https://ncbi.nlm.nih.gov/pubmed/16982800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604069
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