Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA

Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria–localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and i...

Full description

Saved in:
Bibliographic Details
Main Authors: Poncet, Delphine, Pauleau, Anne-Laure, Szabadkai, Gyorgy, Vozza, Angelo, Scholz, Sebastian R., Le Bras, Morgane, Brière, Jean-Jacques, Jalil, Abdelali, Le Moigne, Ronan, Brenner, Catherine, Hahn, Gabriele, Wittig, Ilka, Schägger, Hermann, Lemaire, Christophe, Bianchi, Katiuscia, Souquère, Sylvie, Pierron, Gerard, Rustin, Pierre, Goldmacher, Victor S., Rizzuto, Rosario, Palmieri, Ferdinando, Kroemer, Guido
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064390/
https://ncbi.nlm.nih.gov/pubmed/16982800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604069
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items