Functional interactions within 23S rRNA involving the peptidyltransferase center.

A molecular genetic approach has been employed to investigate functional interactions within 23S rRNA. Each of the three base substitutions at guanine 2032 has been made. The 2032A mutation confers resistance to the antibiotics chloramphenicol and clindamycin, which interact with the 23S rRNA peptid...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Autor principal:	Douthwaite, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1531223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.4.1333-1338.1992
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