Contact-dependent inhibition of EGFR signaling by Nf2/Merlin

The neurofibromatosis type 2 (NF2) tumor suppressor, Merlin, is a membrane/cytoskeleton-associated protein that mediates contact-dependent inhibition of proliferation. Here we show that upon cell–cell contact Merlin coordinates the processes of adherens junction stabilization and negative regulation...

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Bibliographic Details
Main Authors: Curto, Marcello, Cole, Banumathi K., Lallemand, Dominique, Liu, Ching-Hui, McClatchey, Andrea I.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064288/
https://ncbi.nlm.nih.gov/pubmed/17548515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703010
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