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Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms

Axon initial segments (AISs) and nodes of Ranvier are sites of action potential generation and propagation, respectively. Both domains are enriched in sodium channels complexed with adhesion molecules (neurofascin [NF] 186 and NrCAM) and cytoskeletal proteins (ankyrin G and βIV spectrin). We show th...

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Detalles Bibliográficos
Main Authors: Dzhashiashvili, Yulia, Zhang, Yanqing, Galinska, Jolanta, Lam, Isabel, Grumet, Martin, Salzer, James L.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064285/
https://ncbi.nlm.nih.gov/pubmed/17548513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612012
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