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Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms

Axon initial segments (AISs) and nodes of Ranvier are sites of action potential generation and propagation, respectively. Both domains are enriched in sodium channels complexed with adhesion molecules (neurofascin [NF] 186 and NrCAM) and cytoskeletal proteins (ankyrin G and βIV spectrin). We show th...

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Библиографические подробности
Главные авторы: Dzhashiashvili, Yulia, Zhang, Yanqing, Galinska, Jolanta, Lam, Isabel, Grumet, Martin, Salzer, James L.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064285/
https://ncbi.nlm.nih.gov/pubmed/17548513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612012
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