ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

The mammalian ATP-binding cassette transporters A1 and A7 (ABCA1 and -A7) show sequence similarity to CED-7, a Caenorhabditis elegans gene that mediates the clearance of apoptotic cells. Using RNA interference or gene targeting, we show that knock down of macrophage ABCA7 but not -A1 results in defe...

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Detalhes bibliográficos
Main Authors: Jehle, Andreas W., Gardai, Shyra J., Li, Suzhao, Linsel-Nitschke, Patrick, Morimoto, Konosuke, Janssen, William J., Vandivier, R. William, Wang, Nan, Greenberg, Steven, Dale, Benjamin M., Qin, Chunbo, Henson, Peter M., Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064260/
https://ncbi.nlm.nih.gov/pubmed/16908670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200601030
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