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Requirement of dendritic Akt degradation by the ubiquitin–proteasome system for neuronal polarity

Asymmetric distributions of activities of the protein kinases Akt and glycogen synthase kinase 3β (GSK-3β) are critical for the formation of neuronal polarity. However, the mechanisms underlying polarized regulation of this pathway remain unclear. In this study, we report that the instability of Akt...

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Autori principali: Yan, Dong, Guo, Li, Wang, Yizheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064237/
https://ncbi.nlm.nih.gov/pubmed/16864652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200511028
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