Coupling Ca(2+) store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases

Activation of the B cell receptor complex in B lymphocytes causes Ca(2+) release from intracellular stores, which, in turn, activates ion channels known as Icrac. We investigated the mechanisms that link Ca(2+) store release to channel gating in DT40 B lymphocyte cell lines genetically manipulated t...

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Autores principales: Chung, S. Clare, Limnander, Andre, Kurosaki, Tomohiro, Weiss, Arthur, Korenbrot, Juan I.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064139/
https://ncbi.nlm.nih.gov/pubmed/17452533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200702050
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