Mutations causing aminotriazole resistance and temperature sensitivity reside in gyrB, which encodes the B subunit of DNA gyrase.

Certain mutations in gyrA and gyrB, the genes encoding the two subunits of DNA gyrase, are known to influence expression of the his operon (K. E. Rudd and R. Menzel, Proc. Natl. Acad. Sci. USA 84:517-521, 1987). Such mutations lead to a decrease in tRNA(His) levels and consequently to an attenuator-...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Toone, W M, Rudd, K E, Friesen, J D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206392/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1322887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.16.5479-5481.1992
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